Zonisamide
Zonisamide (Zonegran) is approved in the United States for the treatment of focal seizures in people, however it is used successfully to treat generalized seizures in other countries. It appears to be effective for generalized seizures in dogs as well.
Although this drug has not been used extensively, toxicity studies have been done on dogs. The most common side effects appear to be sedation, ataxia and nausea.
This drug is expensive.
Zonisamide Facts:
Mean Elimination Half-Life: 15 to 20 hours
Time to Reach Steady State Concentrations: Unknown
Target Serum Concentration: Unknown
Adverse Effects: The most common side effects in dogs are sedation, ataxia and nausea.
Monitoring: Unknown
